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Eye Care Studies

Mar 28, 2023

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Eye Care Studies

1) Study: Association Between Sleep Positions and Dry Eye Disease (DED).
 
Conclusion: Sleeping on one's stomach may increase the risk of DED symptoms compared to sleeping on one's back or side. Healthcare providers should consider inquiring about sleep position when evaluating patients with DED symptoms, and patients should be advised to avoid sleeping on their stomach if they experience DED symptoms. Further research is needed to elucidate the mechanisms underlying this association. 
 
Source: Eye & Contact Lens. 2021 Sep 1;47(5):346-51.
 
2) Study: Combination Therapy of Meibomian Gland Probing and Intense Pulse Light (IPL) for the Treatment of Dry Eye Disease.
 
Conclusion: Combined Meibomian Gland Probing and IPL therapy is an effective treatment option for DED, as it can improve meibomian gland function, tear film stability, and subjective symptoms while reducing corneal staining. 
 
Source: Contact Lens and Anterior Eye. 2021 Feb 1;44(1):101363.
 
3) Study: Multi-Frequency RF Combined with Intense Pulsed
Light Improves Signs and Symptoms of Dry Eye Disease Due to Meibomian Gland Dysfunction
 
Conclusion: In subjects with moderate to severe DED due to MGD, a series of four treatments consisting of a combination of IPL, multi-frequency RF and MGX decreased symptoms, improved meibum quality and the appearance of eyelids, increased the number of expressible glands, and decreased meibomian gland loss. 
 
Source: Clinical Ophthalmology. 2023;17:3089-3102
 

4) Study: Meibomian Gland Probing (MGP) Stimulates a Proliferative Epithelial Response Resulting in Duct Regeneration

Conclusion: MGP appears to stimulate a proliferative epithelial response characterized by an accelerated more superficial formation of ductal basement membrane with increased duct wall epithelial cell layers (DWECL) as well as distal duct wall thickness (DWT) and lumen area at two separate duct foci. These findings suggest activation of lid margin meibomian gland precursor cells and confirm that MGP stimulates an epithelial regenerative phenomenon, not a fibrotic one.

Source: Clinical Ophthalmology. 2024;18:631-645

5) Study: Is there a relationship between the severity of disease in major depressive disorder (MDD) patients and dry eye disease? 

Conclusion: Dry Eye Disease (DED) was found to be more prevalent in the major depressive disorder (MDD) group. The severity of MDD and DED was found to be correlated. It was observed that patients with higher depression scores had more severe dry eye. As a result, we recommend performing ophthalmic examinations in newly diagnosed MDD patients.

Source: International Ophthalmology. 2024 Mar 29;44(1):163.

6) Study: The impact of Demodex blepharitis on patient symptoms and daily life. 
 
Conclusion: Demodex blepharitis results in a significant negative impact on daily activities, creating a psychosocial and symptomatic burden on patients.

Source: Optometry and Vision Science. 2024 Mar 1;101(3):151-156.